Neurotrophic Factors: Neurotrophin autocrine loops

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Neurotrophic Factors: Neurotrophin autocrine loops

Developing neurons depend on neurotrophins supplied by the tissues they innervate. Before and after this period of target-dependent survival, brain-derived neurotrophic factor also has autocrine actions on some neurons.

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p75 Neurotrophin Receptor in the Skin: Beyond Its Neurotrophic Function

p75 neurotrophin receptor (p75NTR), also known as CD271, is the low-affinity receptor that, together with the tyrosine kinase receptor tropomyosin-receptor kinase (Trk), mediate neurotrophin (NT) functions. Beside their classic role in skin innervation, NT and their receptors constitute a complex cutaneous network associated with a number of autocrine and paracrine activities. In this context, ...

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ژورنال

عنوان ژورنال: Current Biology

سال: 1995

ISSN: 0960-9822

DOI: 10.1016/s0960-9822(95)00144-8